Important figures for their respective clubs, they will have to be careful to avoid a booking in the next fixture. As Premier League clubs head into the busy schedule in December, several stars could find themselves with some extra time off over the festive period.
Alvaro Morata, Harry Kane or Alexis Sanchez are among those listed, while Manchester United are liable to lose up to three important players: Ashley Young, Ander Herrera and Marcos Rojo.
FA rules dictate that once a player receives five bookings, a domestic three-match ban is enforced.
Xhaka - Arsenal - Cautions: 4 - Next match: West Ham United (19/12/2017)
Vincent Kompany - Manchester City - 4 - Leicester City (19/12/2017)
Thomas Smith - Huddersfield Town - 4 - Southampton (23/12/2017)
Steve Cook - AFC Bournemouth - 4 - Chelsea (20/12/2017)
Shola Ameobi - Stoke City - 4 - West Bromwich Albion (23/12/2017)
Phillip Bardsley - Burnley - 4 - Tottenham Hotspur (23/12/2017)
Lewis Dunk - Brighton & Hove Albion - 4 - Watford (23/12/2017)
Leroy Sane - Manchester City - 4 - Leicester City (19/12/2017)
Kevin Wimmer - Stoke City - 4 - West Bromwich Albion (23/12/2017)
Joe Allen - Stoke City - 4 - West Bromwich Albion (23/12/2017)
Jonathan Evans - West Bromwich Albion - 4 - Stoke City (23/12/2017)
Jason Puncheon - Crystal Palace - 4 - Swansea City (23/12/2017)
Jan Vertonghen - Tottenham Hotspur - 4 - Burnley (23/12/2017)
James Mcclean - West Bromwich Albion - 4 - Stoke City (23/12/2017)
Jack Cork - Burnley - 4 - Tottenham Hotspur (23/12/2017)
Idrissa Gueye - Everton - 4 - Chelsea (23/12/2017)
Harry Arter - AFC Bournemouth - 4 - Chelsea (20/12/2017)
Glenn Murray - Brighton & Hove Albion - 4 - Watford (23/12/2017)
Fernandinho - Manchester City - 4 - Leicester City (19/12/2017)
Marcos Rojo - Manchester United - 4 - Bristol City (20/12/2017)
Dejan Lovren - Liverpool - 4 - Arsenal (22/12/2017)
Claudio Yacob - West Bromwich Albion - 4 - Stoke City (23/12/2017)
Ashley Young - Manchester United - 4 - Bristol City (20/12/2017)
Ashley Williams - Everton - 4 - Chelsea (23/12/2017)
Antonio Rudiger - Chelsea - 4 - Bournemouth (20/12/2017)
Anthony Knockaert - Brighton & Hove Albion - 4 - Watford (23/12/2017)
Ander Herrera - Manchester United - 4 - Bristol City (20/12/2017)
Alvaro Morata - Chelsea - 4 - Bournemouth (20/12/2017)
Allan-Romeo Nyom - West Bromwich Albion - 4 - Stoke City (23/12/2017)
Alexis Sanchez - Arsenal - 4 - West Ham United (19/12/2017)