Marseille: Goalkeeper Steve Mandanda (muscle) and midfielder Boubacar Kamara (ankle) are sidelined for the first leg whilst right-back Hiroki Sakai (knee) is a doubt after being taken off during their Ligue 1 match at the weekend.
Salzburg: No major injury concerns for the visitors who will be boosted by the return of midfielder Diadie Samassekou from suspension.
Did you know?
The teams' two group-stage fixtures this term are the only two competitive meetings between the clubs. Salzburg won and drew against Marseille earlier in the tournament.
Score prediction: 3-1
Form:
Possible lineups:
Marseille: Pele; Sarr, Rolando, Amavi; Gustavo, Sanson; Thauvin, Payet, Ocampos; Germain.
Salzburg: Walke; Lainer, Ramalho, Caleta-Car, Ulmer; Haidara, Samassekou, Berisha; Schlager, Dabbur, Hee-Chan.