Napoli left it late to secure a 1-0 victory over Juventus on Sunday to close the gap at the top to just one point with four games remaining.
Juventus arguably have the trickier run in, playing Inter Milan (A), Bologna (H), Roma (A) and Verona (H) whereas their title rivals face Fiorentina (A), Torino (H), Sampdoria (A) and Crotone (H).
Head coach Massimiliano Allegri has already pointed out how Saturday's Derby d'Italia showdown with Inter could be the 'decisive' match in the race of the league crown, with Luciano Spalletti's side and Roma fighting it out for Champions League qualification.
The 'Bianconeri' will have to hold off Napoli without legendary defender Giorgio Chiellini though, who picked up a muscle tear during the defeat and will be sidelined for the next few weeks.
It will be a significant blow for Juventus who lose one of their staple figures at the back and will look to Gonzalo Higuain, Paulo Dybala and Mario Mandzukic to attack relentlessly to keep some of the pressure off a now makeshift defence.
As for their rivals, the win will give Napoli a massive boost going into the final few fixtures and Lorenzo Insigne will hope to be in the thick of things having already scored eight goals and provided nine assists in Serie A this season, stepping up to the plate whilst Dries Mertens goes off the boil.
Mertens 17 league goals have no doubt been instrumental but it is the club's ability to find opportunities from defence, midfield and attack which has given them such a cutting edge this year as they look to win their first league title since 1990.
Whoever, comes out on top, it's going to be a nail-biting finish to the Scudetto.